Other common side effects included flatulence, loss of strength, indigestion, abdominal discomfort, and headache. Nausea/ vomiting occurred in 26% of subjects in the same trial. The most common side effect was diarrhea, which occurred in 53% of metformin-treated subjects involved in a double-blind clinical trial. On the downside, metformin can have a number of unpleasant side effects including diarrhea, nausea, and vomiting. Metformin can help reduce cholesterol and triglyceride levels and does not cause low blood sugar levels as often as some other drugs in its class (like glyburide and glipizide). Another study found that insulin-resistant people given metformin had a 31% less chance of developing diabetes than control subjects with insulin resistance. One study found that metformin was associated with weight loss, better glycemic control, and enhanced insulin sensitivity of visceral fat, which is the deep fat surrounding organs. It helps regulate blood glucose levels by reducing the amount of glucose produced by the liver, limiting the amount of glucose absorbed from food, and helping insulin work better to reduce the amount of glucose in the blood. Metformin is an antidiabetic drug that has been available in the United States since 1995. In addition to using the blood sugar-balancing herbs (such as Glucosol) discussed before, as well as following a low-glycemic diet and an exercise program, your practitioner may wish to give you antidiabetic medication such as metformin, which is known by its brand name Glucophage.

It is your difficulty losing weight, and it is also a sign that you are either becoming insulin resistant, are prediabetic, or are already a type 2 diabetic. At a minimum, you can get a glucose level from a home test kit, but preferably get a fasting glucose and even a glucose tolerance test to evaluate whether your blood sugar is low, normal, high normal. One thing you should consider is getting your blood sugar tested. The endocrine system maintains a delicate balance in the body, and when there is a dysfunction in your thyroid, it can set into motion a host of other imbalances, sensitivities, and abnormalities that all contribute to weight-gain or weight-loss difficulties.